The Holocaust Museum was created by the decision of the board of the Odessa Regional Association of Jews - former prisoners of ghettos and concentration camps and opened on June 22, 2009. The museum collects and preserves materials about the Holocaust during Transnistria, a governorate formed by the Romanian authorities on the territory of part of the occupied Vinnitsa, Odessa and Nikolaev regions, as well as the left-bank part of Moldova.
The Jewish population was sent to concentration camps set up in the countryside. A ghetto was set up in Odessa itself. The Jews of Transnistria were deprived of all civil rights, they were not allowed to choose their place of residence, they were forbidden to leave the ghetto without permission, and Jews were sent to forced labor.
The museum hosts guided tours, meetings of former prisoners, book presentations and screenings of thematic films.